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Most common causes for children include asthma, respiratory tract infections and GERD. An estimation of between one and 21% of children suffer from chronic cough. [2] [32] [33] Causes typically diagnosed include viral bronchitis, post-infectious cough, cough-variant asthma, upper airway cough syndrome, psychogenic cough and GERD.
Protracted bacterial bronchitis in children, is defined as a chronic productive cough with a positive bronchoalveolar lavage that resolves with antibiotics. [ 77 ] [ 78 ] Protracted bacterial bronchitis is usually caused by Streptococcus pneumoniae , non-typable Haemophilus influenzae , or Moraxella catarrhalis . [ 78 ]
The most common symptom of eosinophilic bronchitis is a chronic dry cough lasting more than 6–8 weeks. [3] Eosinophilic bronchitis is also defined by the increased number of eosinophils, a type of white blood cell, in the sputum compared to that of healthy people. [2]
One of the most common causes is Staphylococcus aureus and often follows a recent viral upper respiratory infection. Bacterial tracheitis is a rare complication of influenza infection. [ 4 ] It is the most serious in young children, possibly because of the relatively small size of the trachea that gets easily blocked by swelling.
Other agents that cause this illness include, but are not limited to, human metapneumovirus, influenza, parainfluenza, coronavirus, adenovirus, rhinovirus and mycoplasma. [12] [13] RSV, which is the most common cause of acute bronchiolitis in children.
A common genetic cause is cystic fibrosis, which affects chloride ion transport. [28] Another genetic cause is primary ciliary dyskinesia, a rare disorder that leads to immotility of cilia and can lead to situs inversus. [52] When situs inversus is accompanied by chronic sinusitis and bronchiectasis, this is known as Kartagener's syndrome. [53]
A postinfectious cough is a lingering cough that follows a respiratory tract infection, such as a common cold or flu and lasting up to eight weeks. Postinfectious cough is a clinically recognized condition represented within the medical literature.
At any stage, children with chronic illness can have reduced quality of life, especially if the children or their families are of low socioeconomic status. [ 31 ] [ 32 ] Malnutrition is a greater risk among children with chronic illnesses, and children's physical and cognitive development may be poorly impacted, such as abnormal immune system ...