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Following infection with HIV-1, the rate of clinical disease progression varies between individuals.Factors such as host susceptibility, genetics and immune function, [1] health care and co-infections [2] as well as viral genetic variability [3] may affect the rate of progression to the point of needing to take medication in order not to develop AIDS.
[5] [12] An HIV-positive person on treatment can expect to live a normal life, and die with the virus, not of it. [13] [12] Effective treatment for HIV-positive people (people living with HIV) involves a life-long regimen of medicine to suppress the virus, making the viral load undetectable.
A small percentage of HIV-1 infected individuals retain high levels of CD4+ T-cells without antiretroviral therapy. However, most have detectable viral loads and will eventually progress to AIDS without treatment. These individuals are classified as HIV controllers or long-term nonprogressors (LTNP). People who maintain CD4+ T cell counts and ...
Following infection with HIV, the rate of clinical disease progression varies enormously between individuals. Many factors such as host susceptibility and immune function, [2] [3] [4] health care and co-infections, [5] [6] [7] as well as factors relating to the viral strain [8] [9] may affect the rate of clinical disease progression.
Over the last decade, new HIV infections increased by 24 percent among Latino gay and bisexual men but fell by 18 percent among their white counterparts.
HIV is a member of the genus Lentivirus, [15] part of the family Retroviridae. [16] Lentiviruses have many morphologies and biological properties in common. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. [17]
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