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Benign symmetric lipomatosis, also known as Madelung's disease, is an adult-onset skin condition characterized by extensive symmetric fat deposits in the head, neck, and shoulder girdle area. [1] The symmetrical fat deposits are made of unencapsulated lipomas , which distinguishes it from typical lipomatosis which has encapsulated lipomas that ...
Lipomas are normally removed by simple excision. [27] The removal can often be done under local anesthetic and takes less than 30 minutes. This cures the great majority of cases, with about 1–2% of lipomas recurring after excision. [28] Liposuction is another option if the lipoma is soft and has a small connective tissue component.
Many discrete, encapsulated lipomas form on the trunk and extremities, with relatively few on the head and shoulders. [1] In 1993, a genetic polymorphism within lipomas was localized to chromosome 12q15 , where the HMGIC gene encodes the high-mobility-group protein isoform I-C. [ 2 ] This is one of the most commonly found mutations in solitary ...
The lipomas are well-encapsulated, slow-growing, benign fatty tumors. The distribution is defined as being focused in the trunk of the body and extremities. [2] Familial Multiple Lipomatosis can be identified when multiple lipomas occur in multiple family members that span different generations. [2] Some people may have hundreds of lipomas ...
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Lipomas are usually diagnosed clinically, although imaging (ultrasound, computed tomography, or magnetic resonance imaging) may be utilized to assist with the diagnosis of lipomas in atypical locations. [24] The main treatment for lipomas is surgical excision, after which the tumor is examined with histopathology to confirm the diagnosis. [24]
Angiolipoma is a subcutaneous nodule with vascular structure, having all other features of a typical lipoma. They are commonly painful. [1]: 624 [2] Angiolipomas manifest as multiple painful subcutaneous nodules commonly on the upper limbs. The can occur sporadically, with a family history or after trauma.
Dercum's disease is a rare condition characterized by multiple painful fatty tumors, called lipomas, that can grow anywhere in subcutaneous fat across the body. [1] Sometimes referred as adiposis dolorosa in medical literature, Dercum’s disease is more of a syndrome than a disease (because it has several clinically recognizable features, signs, and symptoms that are characteristic of it and ...