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Lipomas are normally removed by simple excision. [27] The removal can often be done under local anesthetic and takes less than 30 minutes. This cures the great majority of cases, with about 1–2% of lipomas recurring after excision. [28] Liposuction is another option if the lipoma is soft and has a small connective tissue component.
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Many discrete, encapsulated lipomas form on the trunk and extremities, with relatively few on the head and shoulders. [1] In 1993, a genetic polymorphism within lipomas was localized to chromosome 12q15 , where the HMGIC gene encodes the high-mobility-group protein isoform I-C. [ 2 ] This is one of the most commonly found mutations in solitary ...
Lipomas are usually diagnosed clinically, although imaging (ultrasound, computed tomography, or magnetic resonance imaging) may be utilized to assist with the diagnosis of lipomas in atypical locations. [24] The main treatment for lipomas is surgical excision, after which the tumor is examined with histopathology to confirm the diagnosis. [24]
Benign symmetric lipomatosis, also known as Madelung's disease, is an adult-onset skin condition characterized by extensive symmetric fat deposits in the head, neck, and shoulder girdle area. [1] The symmetrical fat deposits are made of unencapsulated lipomas , which distinguishes it from typical lipomatosis which has encapsulated lipomas that ...
The lipomas are well-encapsulated, slow-growing, benign fatty tumors. The distribution is defined as being focused in the trunk of the body and extremities. [2] Familial Multiple Lipomatosis can be identified when multiple lipomas occur in multiple family members that span different generations. [2] Some people may have hundreds of lipomas ...
[13] [14] Adipocytes can exist alone or in small groups between collagen bundles, but they most frequently originate surrounding blood arteries or eccrine glands. [ 9 ] [ 15 ] In certain instances, there is a perivascular infiltration of spindle-shaped and mononuclear cells, as well as an increased density of collagen fibers and fibroblasts .
Angiolipoma is a subcutaneous nodule with vascular structure, having all other features of a typical lipoma. They are commonly painful. [1]: 624 [2] Angiolipomas manifest as multiple painful subcutaneous nodules commonly on the upper limbs. The can occur sporadically, with a family history or after trauma.