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With correct treatment, most cases of amoebic and bacterial dysentery subside within 10 days, and most individuals achieve a full recovery within two to four weeks after beginning proper treatment. If the disease is left untreated, the prognosis varies with the immune status of the individual patient and the severity of disease.
Amoebiasis, or amoebic dysentery, is an infection of the intestines caused by a parasitic amoeba Entamoeba histolytica. [3] [4] Amoebiasis can be present with no, mild, or severe symptoms. [2] Symptoms may include lethargy, loss of weight, colonic ulcerations, abdominal pain, diarrhea, or bloody diarrhea.
Treatment Metronidazole for the invasive trophozoites PLUS a lumenal amoebicide for those still in the intestine. Paromomycin (Humatin) is the luminal drug of choice, since Diloxanide furoate (Furamide) is not commercially available in the United States or Canada (being available only from the Centers for Disease Control and Prevention).
Treatment by use of primitive medicines [ edit ] The Nicobarese people have attested to the medicinal properties found in Glochidion calocarpum , a plant endemic to India, saying that its bark and seed are most effective in curing abdominal disorders associated with amoebiasis .
Paromomycin is an antimicrobial used to treat a number of parasitic infections including amebiasis, giardiasis, leishmaniasis, and tapeworm infection. [3] It is a first-line treatment for amebiasis or giardiasis during pregnancy. [3] Otherwise, it is generally a second line treatment option. [3]
Approximately 90% of patients with E histolytica are asymptomatic. [2] The two most common manifestations of E histolytica include colitis (bloody stool with mucus, abdominal pain, and/or diarrhea), and discovery of a liver abscess on imaging. [2]
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Diloxanide furoate works only in the digestive tract and is a lumenal amebicide. [2] [6] It is considered second line treatment for infection with amoebas when no symptoms are present but the person is passing cysts, in places where infections are not common.