Ads
related to: parafollicular cells in thyroid gland function
Search results
Results From The WOW.Com Content Network
Parafollicular cells, also called C cells, are neuroendocrine cells in the thyroid. They are called C cells because the primary function of these cells is to secrete calcitonin. [1] They are located adjacent to the thyroid follicles and reside in the connective tissue. These cells are large and have a pale stain compared with the follicular cells.
The thyroid gland also produces the hormone calcitonin, which helps regulate blood calcium levels. Parafollicular cells produce calcitonin in response to high blood calcium. Calcitonin decreases the release of calcium from bone, by decreasing the activity of osteoclasts, cells which break down bone.
Calcitonin-producing parafollicular cells are also found along the basement membrane of the thyroid follicle, interspersed between follicular cells; and in spaces between the spherical follicles. Parafollicular cells can be distinguished from follicular cells based on their lighter staining cytoplasm using H&E.
Calcitonin is a 32 amino acid peptide hormone secreted by parafollicular cells (also known as C cells) of the thyroid (or endostyle) in humans and other chordates [5] in the ultimopharyngeal body. [6] It acts to reduce blood calcium (Ca 2+), opposing the effects of parathyroid hormone (PTH). [7]
Thyroid gland. follicular cells of the thyroid gland produce and secrete T 3 and T 4 in response to elevated levels of TRH, produced by the hypothalamus, and subsequent elevated levels of TSH, produced by the anterior pituitary gland, which further regulates the metabolic activity and rate of all cells, including cell growth and tissue ...
The ultimopharyngeal body, or ultimobranchial body or ultimobranchial gland is a small organ found in the neck region of many animals. In humans, it develops from the fourth pharyngeal pouch into the parafollicular cells of the thyroid to produce calcitonin. It may not develop in DiGeorge syndrome.
Thyroid gland Follicular cell; Parafollicular cell [3] Parathyroid gland. Parathyroid chief cell; Oxyphil cell; Thymus gland. Thymic epithelial cell; Hindgut/cloaca.
Calcitonin, produced by the parafollicular cells (C cells) of the thyroid gland in response to rising blood calcium levels, depresses blood calcium levels by inhibiting bone matrix resorption and enhancing calcium deposit in bones. Excessive secretion cause hyperthyroidism and deficiency cause hypothyroidism.