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Oxytetracycline, like other tetracyclines, is used to treat many infections, both common and rare.Its better absorption profile makes it preferable to tetracycline for moderately severe acne at a dosage of 250–500 mg four times a day for usually six to eight weeks at a time, but alternatives should be sought if no improvement occurs by three months.
Polymyxin B/trimethoprim, sold under the brand name Polytrim is an antimicrobial solution for topical ophthalmic use in the treatment of acute bacterial conjunctivitis and blepharoconjunctivitis. [1] In 2022, it was the 252nd most commonly prescribed medication in the United States, with more than 1 million prescriptions. [2] [3]
Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. [5] This includes use as an eye ointment to treat conjunctivitis. [6] By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever. [5]
Other side effects include poor tooth development if used by children less than eight years of age, kidney problems, and sunburning easily. [3] Use during pregnancy may harm the baby. [3] It works by inhibiting protein synthesis in bacteria. [3] Tetracycline was patented in 1953 [6] and was approved for prescription use in 1954.
But ultimately oxytetracycline (terramycin) was isolated in 1949 by Alexander Finlay from a soil sample collected on the grounds of a factory in Terre Haute, Indiana. [43] It came from a similar soil bacterium named Streptomyces rimosus. [44] From the beginning, terramycin was a molecule enveloped in controversy.
Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries. [ 1 ] [ 2 ] It contains the three antibiotics neomycin , polymyxin B , and bacitracin . [ 1 ]