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Polymyxin B/trimethoprim, sold under the brand name Polytrim is an antimicrobial solution for topical ophthalmic use in the treatment of acute bacterial conjunctivitis and blepharoconjunctivitis. [1] In 2022, it was the 252nd most commonly prescribed medication in the United States, with more than 1 million prescriptions. [2] [3]
Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries. [1] [2] It contains the three antibiotics neomycin, polymyxin B, and bacitracin. [1] It is for topical use. [3] [4]
Oxytetracycline, like other tetracyclines, is used to treat many infections, both common and rare.Its better absorption profile makes it preferable to tetracycline for moderately severe acne at a dosage of 250–500 mg four times a day for usually six to eight weeks at a time, but alternatives should be sought if no improvement occurs by three months.
Though Polysporin is marketed in the US, it holds a much smaller market share than in Canada and acts as a substitute to Johnson & Johnson's Neosporin for those allergic to the antibiotic neomycin. However, allergy to bacitracin/polymyxin B has also been reported. [2] There is also an ophthalmological ointment, eye and ear drops.
As bacitracin zinc salt, in combination with other topical antibiotics (usually polymyxin B and neomycin) as an ointment ("triple antibiotic ointment," with the brand name Neosporin), it is used for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections. A non-ointment form of ...
Figure 1.0 - Basic anatomical features of the human eye. Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]