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  2. Factor V Leiden - Wikipedia

    en.wikipedia.org/wiki/Factor_V_Leiden

    Factor V Leiden is the most common hereditary hypercoagulability (prone to clotting) disorder amongst ethnic Europeans. [ 3 ] [ 4 ] [ 5 ] It is named after the Dutch city of Leiden , where it was first identified in 1994 by Rogier Maria Bertina under the direction of (and in the laboratory of) Pieter Hendrik Reitsma. [ 6 ]

  3. Factor V - Wikipedia

    en.wikipedia.org/wiki/Factor_V

    Coagulation factor V (Factor V), also less commonly known as proaccelerin or labile factor, is a protein involved in coagulation, encoded, in humans, by F5 gene. [5] In contrast to most other coagulation factors, it is not enzymatically active but functions as a cofactor . [ 5 ]

  4. Activated protein C resistance - Wikipedia

    en.wikipedia.org/wiki/Activated_protein_C_resistance

    APC resistance is the inability of protein C to cleave Factor Va and/or Factor VIIIa, which allows for longer duration of thrombin generation and may lead to a hypercoagulable state. This may be hereditary or acquired. [4] The best known and most common hereditary form is Factor V Leiden, which is responsible for more than 95% of cases. [5]

  5. What you need to know about factor V Leiden - a blood ... - AOL

    www.aol.com/news/know-factor-v-leiden-blood...

    Factor V Leiden is an inherited blood clotting disorder. It can cause life-threatening clots in the body and complications during pregnancy. What you need to know about factor V Leiden - a blood ...

  6. Activated protein C resistance test - Wikipedia

    en.wikipedia.org/wiki/Activated_protein_C...

    The activated protein C resistance (APCR) test is a coagulation test used in the evaluation and diagnosis of activated protein C (APC) resistance, a form of hypercoagulability.

  7. Thrombophilia - Wikipedia

    en.wikipedia.org/wiki/Thrombophilia

    The exact prevalence of protein S deficiency in the population is unknown; it is found 1.3–5% of people with thrombosis. [14] The minor ("type 2") thrombophilias are much more common. Factor V Leiden is present in 5% of the population of Northern European descent, but much rarer in those of Asian or African extraction.

  8. List of hematologic conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_hematologic_conditions

    Protein C deficiency is a rare genetic trait that predisposes to thrombotic disease. [83] Protein S deficiency: Factor V Leiden: Thrombocytosis: Idiopathic thrombocytopenic purpura: D69.3: 6673: D016553 Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low platelet count (thrombocytopenia) of no known cause . Recurrent ...

  9. Sticky platelet syndrome - Wikipedia

    en.wikipedia.org/wiki/Sticky_platelet_syndrome

    It can present in conjunction with protein S deficiency and factor V Leiden. [8] It is not currently known if sticky platelet syndrome is a distinct condition, or if it represents part of the presentation of a more well characterized coagulation disorder. SPS has not been widely studied [9] and is not widely known. [10]

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