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  2. Your Gout Guide: From Symptoms to Treatment - AOL

    www.aol.com/gout-guide-symptoms-treatment...

    Gout in hands is less common but can happen. In this situation, it usually affects small joints in the fingers. ... If you have frequent gout flares, gout associated with tophi, or joint damage ...

  3. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    Arms and hands of a 50-year-old man, showing large tophi of sodium urate affecting the elbow, knuckles, and finger joints. The crystallization of uric acid , often related to relatively high levels in the blood, is the underlying cause of gout.

  4. Tophus - Wikipedia

    en.wikipedia.org/wiki/Tophus

    A tophus (Latin: "stone", pl.: tophi) is a deposit of monosodium urate crystals, in people with longstanding high levels of uric acid (urate) in the blood, a condition known as hyperuricemia. Tophi are pathognomonic for the disease gout. Most people with tophi have had previous attacks of acute arthritis, eventually leading to the formation of ...

  5. Acquired hand deformity - Wikipedia

    en.wikipedia.org/wiki/Acquired_hand_deformity

    Besides this, gouty arthritis can be associated with tophi deposits in the joints of the hand. [22] Gout can induce pain and swelling. [24] Bony enlargements resulting from osteoarthritis may cause pain, as well as several types of joint issues. [5]

  6. Hyperuricemia - Wikipedia

    en.wikipedia.org/wiki/Hyperuricemia

    Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [4] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...

  7. Cold hands are common in winter. When are they a sign of a ...

    www.aol.com/lifestyle/cold-hands-common-winter...

    The hands typically get cold when the body or the hand specifically is exposed to cold.” Most of the time cold hands aren’t a cause for concern — they’re simply the result of less blood ...

  8. A.J. Brown felt like a 'paid actor' in Eagles' Super Bowl ...

    www.aol.com/j-brown-felt-paid-actor-162919385.html

    Philadelphia Eagles' A.J. Brown speaks during an NFL football news conference in Philadelphia, Thursday, Jan. 30, 2025, ahead of Super Bowl LIX against the Kansas City Chiefs.

  9. Pegloticase - Wikipedia

    en.wikipedia.org/wiki/Pegloticase

    Pegloticase (trade name Krystexxa) is a medication for the treatment of severe, treatment-refractory, chronic gout. It is a third line treatment in those in whom other treatments are not effective or are not tolerated. [2] The drug is administered by infusion intravenously. Since October 2023, Amgen Inc. has been the marketer of pegloticase in ...