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Phytomenadione, also known as vitamin K 1 or phylloquinone, is a vitamin found in food and used as a dietary supplement. [6] [7] It is on the World Health Organization's List of Essential Medicines. [8] It is used to treat certain bleeding disorders, [7] including warfarin overdose, vitamin K deficiency, and obstructive jaundice. [7]
[2] [3] Vitamin K injections are administered to newborns as a preventative measure to reduce the risk of hemorrhagic disease of the newborn (HDN). [ 4 ] [ 5 ] The coagulation pathway helps the body stop active bleeds by using vitamin K dependent clotting factors (factors II, VII, IX, and X) which are synthesized by the liver.
The menadione core is apparent in the structure of vitamin K. It is an intermediate in the chemical synthesis of vitamin K by first reduction to the diol menadiol, which is susceptible to coupling to the phytol. [10] It is a useful intermediate for organic synthesis in general, as it can be made and modified in a number of ways. [11]
Vitamin K is a family of structurally similar, fat-soluble vitamers found in foods and marketed as dietary supplements. [1] The human body requires vitamin K for post-synthesis modification of certain proteins that are required for blood coagulation ("K" from Danish koagulation, for "coagulation") or for controlling binding of calcium in bones and other tissues. [2]
“People with malabsorption in their stomach or intestines, such as patients after weight loss surgery or patients with gastrointestinal issues, need robust vitamin supplementation to maintain ...
Neonatal isoerythrolysis (NI), also known as hemolytic icterus or hemolytic anemia, [1] is a disease most commonly seen in kittens and foals, but has also been reported in puppies. It occurs when the mother has antibodies against the blood type of the newborn. A 7 day old foal with neonatal isoerythrolysis.
Newborn infants have low stores of vitamin K, and human breast milk has low concentrations of the vitamin. This combination can lead to vitamin K deficiency and later onset bleeding. Vitamin K deficiency leads to the risk of blood coagulation problems due to impaired production of clotting factors II, VII, IX, X, protein C and protein S by the ...
During growth, young dogs are more susceptible to infection, but the addition of proper levels of vitamin E to the diet reduces free radical oxidative damage and leads to an increase in immunity. Calcium and phosphorus, in the appropriate amounts and ratio, aid in proper bone and cartilage growth and maturation.