Ads
related to: clinical pharmacokinetics handbook
Search results
Results From The WOW.Com Content Network
Clinical Pharmacokinetics is a peer-reviewed medical journal published by Adis International (Springer Nature) that covers topics related to pharmacokinetics.According to the Journal Citation Reports, the journal has a 2023 Impact Factor™ of 4.6 ranked 77 of 277 journals in the Pharmacology & Pharmacy category [Clarivate Analytics]; 2023 CiteScore™ of 8.8 ranked 81 of 272 journals in the ...
The use of trapezoidal rule in AUC calculation was known in literature by no later than 1975, in J.G. Wagner's Fundamentals of Clinical Pharmacokinetics. A 1977 article compares the "classical" trapezoidal method to a number of methods that take into account the typical shape of the concentration plot, caused by first-order kinetics. [8]
Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific substance after administration. [1]
Rowland has published over 270 research articles in international peer-reviewed journals, and over 60 book chapters and conference reports. He co-authored with Thomas Tozer two standard textbooks: Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, now in its 5th edition, and Essentials of Pharmacokinetics and Pharmacodynamics.
Pharmacokinetics simulation gives an insight to drug efficacy and safety before exposure of individuals to the new drug that might help to improve the design of a clinical trial. Pharmacokinetics simulations help in addition in therapy planning, to stay within the therapeutic range under various physiological and pathophysiological conditions ...
Goodman & Gilman's The Pharmacological Basis of Therapeutics, commonly referred to as the Blue Bible or Goodman & Gilman, is a textbook of pharmacology originally authored by Louis S. Goodman and Alfred Gilman. First published in 1941, the book is in its 14th edition (as of 2022), and has the reputation of being the "bible of pharmacology".
Physiologically based pharmacokinetic (PBPK) modeling is a mathematical modeling technique for predicting the absorption, distribution, metabolism and excretion (ADME) of synthetic or natural chemical substances in humans and other animal species.
The related pharmacokinetic parameter t max is the time at which the C max is observed. [ 2 ] After an intravenous administration, C max and t max are closely dependent on the experimental protocol, since the concentrations are always decreasing after the dose.