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The first-line treatment is generally given to patients as an initial antiretroviral therapy and is the cheapest of the stages of treatments. [1] The first-line antiretroviral drug treatment as recommended by the World Health Organization (WHO) involves TDF (tenofovir), 3TC (lamivudine) or FTC (emtricitabine), and EFV (efavirenz) or dolutegravir (DTG).
Antiretroviral drugs are used to manage HIV/AIDS. Multiple antiretroviral drugs are often combined into a single pill in order to reduce pill burden. Some of these combinations are complete single-tablet regimens; the others must be combined with additional pills to make a treatment regimen.
Truvada was previously only approved by the U.S. Food and Drug Administration (FDA) to treat HIV in those already infected. In 2012, the FDA approved the drug for use as pre-exposure prophylaxis (PrEP), based on growing evidence that the drug was safe and effective at preventing HIV in populations at increased risk of infection. [41]
The first HIV drug, which came out in 1987, blocked nucleoside reverse transcriptase, an enzyme HIV uses to replicate. A few similar medications followed over the next few years, but the fast ...
Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.
“The results of the drug’s clinical trials, he said, “must be to the benefit of all people at risk for HIV, including those with cost-related hurdles to state-of-the-art prevention and care.”
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