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  2. Ribose - Wikipedia

    en.wikipedia.org/wiki/Ribose

    L-Ribose Fischer Projection. Ribose is a simple sugar and carbohydrate with molecular formula C 5 H 10 O 5 and the linear-form composition H−(C=O)−(CHOH) 4 −H. The naturally occurring form, d-ribose, is a component of the ribonucleotides from which RNA is built, and so this compound is necessary for coding, decoding, regulation and expression of genes.

  3. Nucleic acid sequence - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_sequence

    Nucleic acids consist of a chain of linked units called nucleotides. Each nucleotide consists of three subunits: a phosphate group and a sugar (ribose in the case of RNA, deoxyribose in DNA) make up the backbone of the nucleic acid strand, and attached to the sugar is one of a set of nucleobases.

  4. Nucleic acid structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_structure

    B-DNA base pairs are nearly perpendicular to the helix axis. The sugar pucker which determines the shape of the a-helix, whether the helix will exist in the A-form or in the B-form, occurs at the C2'-endo. [13] A-DNA, is a form of the DNA duplex observed under dehydrating conditions. It is shorter and wider than B-DNA.

  5. Nucleic acid tertiary structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_tertiary...

    Ribose Zippers: View of a canonical ribose zipper between two RNA backbones. [33] The ribose zipper is an RNA tertiary structural element in which two RNA chains are held together by hydrogen bonding interactions involving the 2’OH of ribose sugars on different strands. The 2'OH can behave as both hydrogen bond donor and acceptor, which ...

  6. Ribose-seq - Wikipedia

    en.wikipedia.org/wiki/Ribose-seq

    The ribose-seq adaptor is made up of one dT (deoxyribonucleotide thymine) followed by an annealing sequence, two primer sequences, and a unique molecular identifier (UMI). To prepare the ribose-seq adaptor, the three oligonucleotides (oligos) are added to a solution and heated to 95-100 °C. At this temperature, the oligo sequences anneal to ...

  7. Ribonucleotide - Wikipedia

    en.wikipedia.org/wiki/Ribonucleotide

    DNA is defined by containing 2'-deoxy-ribose nucleic acid while RNA is defined by containing ribose nucleic acid. [1] In some occasions, DNA and RNA may contain some minor bases. Methylated forms of the major bases are most common in DNA. In viral DNA, some bases may be hydroxymethylated or glucosylated.

  8. Directionality (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Directionality_(molecular...

    In a single strand of DNA or RNA, the chemical convention of naming carbon atoms in the nucleotide pentose-sugar-ring means that there will be a 5′ end (usually pronounced "five-prime end"), which frequently contains a phosphate group attached to the 5′ carbon of the ribose ring, and a 3′ end (usually pronounced "three-prime end"), which ...

  9. Nucleic acid structure determination - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_structure...

    X-ray crystallography is not common for nucleic acids alone, since neither DNA nor RNA readily form crystals. This is due to the greater degree of intrinsic disorder and dynamism in nucleic acid structures and the negatively charged (deoxy)ribose-phosphate backbones, which repel each other in close proximity.