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The rate of mean blood flow depends on both blood pressure and the resistance to flow presented by the blood vessels. Mean blood pressure decreases as the circulating blood moves away from the heart through arteries and capillaries due to viscous losses of energy.
In the lungs, special mechanisms have been adapted to meet the needs of increased necessity of blood flow during exercise. When the heart rate increases and more blood must flow through the lungs, capillaries are recruited and are also distended to make room for increased blood flow. This allows blood flow to increase while resistance decreases.
At high temperatures the minimum flow rate will decrease and the capillary will expand. This allows heat transfer through the increased surface area of the inner capillary lining and through increased blood flow. At low temperatures the minimum flow rate will increase and the capillary will constrict. This restricts blood flow and decreases the ...
The rate at which fluid is filtered across vascular endothelium (transendothelial filtration) is determined by the sum of two outward forces, capillary pressure and interstitial protein osmotic pressure (), and two absorptive forces, plasma protein osmotic pressure and interstitial pressure (). The Starling equation describes these forces in ...
Capillary walls allow the free flow of almost every substance in plasma. [6] The plasma proteins are the only exception, as they are too big to pass through. [5] The minimum number of un-absorbable plasma proteins that exit capillaries enter lymphatic circulation for returning later on to those blood vessels.
A Lindbergh perfusion pump, c. 1935, an early device for simulating natural perfusion. Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, [1] usually referring to the delivery of blood to a capillary bed in tissue.
Blood viscosity is a measure of the resistance of blood to flow. It can also be described as the thickness and stickiness of blood. This biophysical property makes it a critical determinant of friction against the vessel walls, the rate of venous return, the work required for the heart to pump blood, and how much oxygen is transported to tissues and organs.
Differences in vascular permeability between normal tissue and a tumor. Vascular permeability, often in the form of capillary permeability or microvascular permeability, characterizes the capacity of a blood vessel wall to allow for the flow of small molecules (drugs, nutrients, water, ions) or even whole cells (lymphocytes on their way to the site of inflammation) in and out of the vessel.