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Magnetic resonance elastography (MRE) is a form of elastography that specifically leverages MRI to quantify and subsequently map the mechanical properties (elasticity or stiffness) of soft tissue. First developed and described at Mayo Clinic by Muthupillai et al. in 1995, MRE has emerged as a powerful, non-invasive diagnostic tool, namely as an ...
Tomoelastography of the abdomen; upper a healthy state, lower with malignancy.. Tomoelastography (from ancient Greek τόμος tomos, “slice” and elastography – imaging of viscoelastic properties) is a medical imaging technique that provides quantitative maps of the mechanical properties of biological soft tissues with high spatial resolution (called elastograms).
In Bristol University's study Children of the 90s, 2.5% of 4,000 people born in 1991 and 1992 were found by ultrasound scanning at the age of 18 to have non-alcoholic fatty liver disease; five years later transient elastography found over 20% to have the fatty deposits on the liver of steatosis, indicating non-alcoholic fatty liver disease ...
Fatty liver disease (FLD), also known as hepatic steatosis and steatotic liver disease (SLD), is a condition where excess fat builds up in the liver. [1] Often there are no or few symptoms. [ 1 ] [ 2 ] Occasionally there may be tiredness or pain in the upper right side of the abdomen . [ 1 ]
Liver biopsy is often required for the diagnosis of a liver problem (jaundice, abnormal blood tests) where blood tests, such as hepatitis A serology, have not been able to identify a cause. It is also required if hepatitis is possibly the result of medication , but the exact nature of the reaction is unclear.
The typical test temperature is 37 °C, but different temperatures can be selected, e.g. for patients with hypothermia. [ 7 ] In contrast to thrombelastography with its pendulum-like principle, the design of the TEM viscoelastic detection system (figure 1) makes it quite robust and insensitive against mechanical shocks or vibrations.
Because the liver is important for making proteins used in blood clotting, coagulation-related studies are often carried out, especially the prothrombin time. In people with fatty liver with associated inflammatory injury (steatohepatitis) blood tests are usually used to rule out certain types of viral hepatitis and autoimmune diseases.
Liver cirrhosis on CT imaging of the abdomen in transverse view. Portable ultrasound is a low cost tool to identify the sign of liver surface nodularity with a good diagnostic accuracy. [71] Cirrhosis is also diagnosable through a variety of new elastography techniques. [72] [73] When a liver becomes cirrhotic it will generally become stiffer ...