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The IL-5 receptor is composed of an α and a βc chain. [23] The α subunit is specific for the IL-5 molecule, whereas the βc subunit also recognised by interleukin 3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF). [23] [24] Glycosylation of the Asn196 residue of the Rα subunit appears to be essential for binding of IL-5 ...
The interleukin-5 receptor is a type I cytokine receptor.It is a heterodimer of the interleukin 5 receptor alpha subunit and CSF2RB. [1] [2]The IL-5 receptor (IL-5R) belongs to the type I cytokine receptor family and is a heterodimer composed of two polypeptide chains, one α subunit, which binds IL-5 and confers upon the receptor cytokine specificity, and one β subunit, which contains the ...
Interleukin 5 (IL5), also known as eosinophil differentiation factor (EDF), is a lineage-specific cytokine for eosinophilpoiesis. [ 17 ] [ 18 ] It regulates eosinophil growth and activation, [ 17 ] and thus plays an important role in diseases associated with increased levels of eosinophils, including asthma. [ 18 ]
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5).
Interferon type I: All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α/β receptor that consists of IFNAR1 and IFNAR2 chains. [5] The type I interferons present in humans are IFN-α, IFN-β, IFN-ε, IFN-κ and IFN-ω. [6]
Interleukin-2 (IL-2) is an interleukin, which is a type of cytokine signaling molecule forming part of the immune system. It is a 15.5–16 kDa protein [ 5 ] that regulates the activities of white blood cells (leukocytes, often lymphocytes ) that are responsible for immunity.
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IL13RA2 - Interleukin-13 receptor subunit alpha-2 CD214 not assigned CD215: IL15RA - Interleukin 15 receptor, alpha subunit CD216 not assigned CD217: IL17R - Interleukin-17 receptor; a cytokine receptor which binds interleukin 17A. CD218a: IL18R1 - interleukin-18 receptor 1 CD218b: IL18RAP - Interleukin 18 receptor accessory protein.