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Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. [1] [2] If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. [3]
Signs and symptoms [ edit ] Autoimmune hypophysitis can lead to deficiencies in one or more pituitary hormones, causing central diabetes insipidus if the posterior pituitary gland is affected as well as central adrenal insufficiency and central hypothyroidism if the anterior pituitary gland is affected. [ 1 ]
The first reported case was in 1962, with a 22-year-old who died of adrenal insufficiency 14 months after giving birth to her second child. Her symptoms began 3 months postpartum, with lassitude (weakness/lack of energy), goitre (iodine deficiency) and amenorrhea (absence of a menstrual period).
The most common symptom, in over 95% of cases, is a sudden-onset headache located behind the eyes or around the temples. It is often associated with nausea and vomiting . [ 1 ] [ 2 ] [ 3 ] Occasionally, the presence of blood leads to irritation of the lining of the brain , which may cause neck rigidity and intolerance to bright light, as well ...
Now, new research finds that women who use hormone therapy after age 65 are usually fine to do just that — but the dose and timing of the treatment matter. The study, which was published in ...
Poor pituitary production of LH is thought to be implicated in obesity-associated testosterone deficiency. One study revealed that altering a BMI from 30 to 25 kg/m2 could result in a 13 percent ...
In some cases, a woman with Sheehan syndrome may be relatively asymptomatic initially; therefore, the diagnosis would not be made until years later when features of hypopituitarism become evident. [7] In rare instances this syndrome can present acutely with unstable vital signs, dangerously low blood glucose levels, heart failure, or even ...
Hypoprolactinemia can result from autoimmune disease, [2] hypopituitarism, [1] growth hormone deficiency, [2] hypothyroidism, [2] excessive dopamine action in the tuberoinfundibular pathway and/or the anterior pituitary, and ingestion of drugs that activate the D 2 receptor, such as direct D 2 receptor agonists like bromocriptine and pergolide, and indirect D 2 receptor activators like ...