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After March 1952 Franklin concentrated on the X-ray data for the A-form of less hydrated DNA while Wilkins tried to work on the hydrated B-form. Wilkins was handicapped because Franklin had all of the good DNA. Wilkins got new DNA samples, but it was not as good as the original sample he had obtained in 1950 and which Franklin continued to use.
Rosalind Franklin joined King's College London in January 1951 to work on the crystallography of DNA. By the end of that year, she established two important facts: one is that phosphate groups, which are the molecular backbone for the nucleotide chains, lie on the outside (it was a general consensus at the time that they were at the inside); and the other is that DNA exists in two forms, a ...
(The biological functions of A-DNA were discovered only 60 years later. [69]) Because of the intense personality conflict developing between Franklin and Wilkins, Randall divided the work on DNA. Franklin chose the data rich "A" form while Wilkins selected the "B" form. [70] [71] A satirical death note of A-DNA helix by Franklin and Gosling.
Photo 51 is an X-ray based fiber diffraction image of a paracrystalline gel composed of DNA fiber [1] taken by Raymond Gosling, [2] [3] a postgraduate student working under the supervision of Maurice Wilkins and Rosalind Franklin at King's College London, while working in Sir John Randall's group.
It's 65 years since the structure of DNA was first published, but the woman who made that possible remains unknown to many people. Rosalind Franklin still doesn't get the recognition she deserves ...
DNA model built by Crick and Watson in 1953, in the Science Museum, London. In mid-March 1953, Watson and Crick deduced the double helix structure of DNA. [13] Crucial to their discovery were the experimental data collected at King's College London—mainly by Rosalind Franklin for which they did not provide proper attribution.
In the 1940s and early 1950s, experiments pointed to DNA as the portion of chromosomes (and perhaps other nucleoproteins) that held genes. A focus on new model organisms such as viruses and bacteria, along with the discovery of the double helical structure of DNA in 1953, marked the transition to the era of molecular genetics.
The film manages to convey the loneliness and competitiveness of scientific research but also educates the viewer about how DNA's structure was discovered. It explores the tension between the patient, dedicated laboratory work of Franklin and the sometimes uninformed intuitive leaps of Watson and Crick, against a background of institutional ...