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However, the neurotoxic side effects occurring at the required dosages have prevented the widespread use of metronidazole as an adjuvant agent in radiation therapy. [32] However, other nitroimidazoles derived from metronidazole such as nimorazole with reduced electron affinity showed less serious neuronal side effects and have found their way ...
Diagnosis is suspected based on the symptoms, and may be verified by testing the vaginal discharge and finding a higher than normal vaginal pH, and large numbers of bacteria. [6] BV is often confused with a vaginal yeast infection or infection with Trichomonas. [7] Usually treatment is with an antibiotic, such as clindamycin or metronidazole.
Metronidazole is an antibiotic with an off-label use in eradicating H. pylori for treating gastric ulceration. Resistance of metronidazole is above 15% worldwide. [32] It is likely to be resistant so is not the first line choice of treatment. [44]
Clinical data for other vaginal infections are more limited. [5] Side effects of vaginal boric acid may include watery discharge, burning, itching, redness, bleeding, and erosive changes. [5] They are usually mild and temporary. [5] Boric acid can produce toxic effects, including death, if taken orally and/or at very high doses.
The vaginal flora consists of those organisms which generally do not cause symptoms and is dominated mainly by Lactobacillus species. [13] Disruption of the normal flora can cause a vaginal yeast infection. Vaginal yeast infection can affect women of all ages and is very common. The yeast Candida albicans is the most common cause of vaginitis ...
It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock itch. [2] It can be taken by mouth or applied as a cream to the skin or in the vagina. [2] Common side effects when taken by mouth include nausea and itchiness. [2]
Administering a vaginal tablet without an applicator. Intravaginal administration is a route of administration where the substance is applied inside the vagina . Pharmacologically , it has the potential advantage to result in effects primarily in the vagina or nearby structures (such as the vaginal portion of cervix ) with limited systemic ...
The most common side effects of terconazole include headaches, vulvar/vaginal irritation, rash, itching, burning or discomfort. [7] Other side effects may include abdominal pain or cramps, dysmenorrhea , chills , fever and allergic reactions.