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Histopathology – the microscopic examination of stained tissue sections using histological techniques. The standard stains are haematoxylin and eosin , but many others exist. The use of haematoxylin and eosin-stained slides to provide specific diagnoses based on morphology is considered to be the core skill of anatomic pathology.
Since more DNA is unfolded and being expressed, the nucleus will be darker and less uniform, larger than in normal cells, and often show a bright-red nucleolus. While the cytologist's primary responsibility is to discern whether cancerous or precancerous pathology is present in the cellular sample analysed, other pathologies may be seen such as:
Histopathology (compound of three Greek words: ἱστός histos 'tissue', πάθος pathos 'suffering', and -λογία-logia 'study of') is the microscopic examination of tissue in order to study the manifestations of disease.
Artifacts are structures or features in tissue that interfere with normal histological examination. Artifacts interfere with histology by changing the tissues appearance and hiding structures. Tissue processing artifacts can include pigments formed by fixatives, [ 12 ] shrinkage, washing out of cellular components, color changes in different ...
Histopathology refers to the microscopic examination of various forms of human tissue. Specifically, in clinical medicine, histopathology refers to the examination of a biopsy or surgical specimen by a pathologist, after the specimen has been processed and histological sections have been placed onto glass slides. [ 17 ]
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. [1] [2] All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. [3] Cell biology is the study of the structural and functional ...
Laboratory technologists may flag abnormal samples for pathologist review. The pathologist may recommend additional testing, such as flow cytometry to identify lymphoma or leukemia cells, or cytology to characterize solid tumor cells.
The cells of meristematic tissue are similar in structure and have a thin and elastic primary cell wall made of cellulose. They are compactly arranged without inter-cellular spaces between them. Each cell contains a dense cytoplasm and a prominent cell nucleus. The dense protoplasm of meristematic cells contains very few vacuoles.