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  2. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [ 1 ] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.

  3. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    Major depressive disorder (MDD), also known as clinical depression, is a mental disorder [ 9 ] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [ 10 ] the term was adopted by the American ...

  4. Depression (mood) - Wikipedia

    en.wikipedia.org/wiki/Depression_(mood)

    Depressed mood is a symptom of some mood disorders, also categorized and called depression, such as major depressive disorder, bipolar disorder and dysthymia; [7] it is a normal temporary reaction to life events, such as the loss of a loved one; and it is also a symptom of some physical diseases and a side effect of some drugs and medical ...

  5. Evolutionary approaches to depression - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_approaches_to...

    Major depression (also called "major depressive disorder", "clinical depression" or often simply "depression") is a leading cause of disability worldwide, and in 2000 was the fourth leading contributor to the global burden of disease (measured in DALYs); it is also an important risk factor for suicide. [1]

  6. Dennis S. Charney - Wikipedia

    en.wikipedia.org/wiki/Dennis_S._Charney

    Dennis S. Charney is an American biological psychiatrist and researcher, with expertise in the neurobiology and treatment of mood and anxiety disorders. [1] He is the author of Neurobiology of Mental Illness, The Physician's Guide to Depression and Bipolar Disorders and Molecular Biology for the Clinician, as well as the author of over 600 original papers and chapters.

  7. Depression and immune function - Wikipedia

    en.wikipedia.org/wiki/Depression_and_immune_function

    Major depression is often associated with biomarkers indicative of inflammatory responses, with interleukin-6, interleukin-1, interleukin-2 receptor, tumor necrosis factor alpha, C-reactive protein, and monocyte chemotactic protein-1 all being found to be elevated in those with depression.

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