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synthesis. In chemistry, de novo synthesis (from Latin 'from the new') is the synthesis of complex molecules from simple molecules such as sugars or amino acids, as opposed to recycling after partial degradation. For example, nucleotides are not needed in the diet as they can be constructed from small precursor molecules such as formate and ...
A de novo mutation (DNM) is any mutation or alteration in the genome of an individual organism (human, animal, plant, microbe, etc.) that was not inherited from its parents. This type of mutation spontaneously occurs during the process of DNA replication during cell division. De novo mutations, by definition, are present in the affected ...
Mode (s) Single-player, multiplayer. Terraria ( / təˈrɛəriə / ⓘ tə-RAIR-ee-ə[1]) is a 2011 action-adventure sandbox game developed by Re-Logic. The game was first released for Windows and has since been ported to other PC and console platforms. The game features exploration, crafting, building, painting, and combat with a variety of ...
De novo gene birth. De novo. gene birth. Novel genes can emerge from ancestrally non-genic regions through poorly understood mechanisms. (A) A non-genic region first gains transcription and an open reading frame (ORF), in either order, facilitating the birth of a de novo gene. The ORF is for illustrative purposes only, as de novo genes may also ...
De novo sequence assemblers. De novo sequence assemblers are a type of program that assembles short nucleotide sequences into longer ones without the use of a reference genome. These are most commonly used in bioinformatic studies to assemble genomes or transcriptomes. Two common types of de novo assemblers are greedy algorithm assemblers and ...
De novo peptide sequencing. In mass spectrometry, de novo peptide sequencing is the method in which a peptide amino acid sequence is determined from tandem mass spectrometry. Knowing the amino acid sequence of peptides from a protein digest is essential for studying the biological function of the protein. In the old days, this was accomplished ...
In computational biology, de novo protein structure prediction refers to an algorithmic process by which protein tertiary structure is predicted from its amino acid primary sequence. The problem itself has occupied leading scientists for decades while still remaining unsolved. According to Science, the problem remains one of the top 125 ...
De novo protein design, the creation of a protein sequence that is not based on existing, natural sequences. De novo protein structure prediction, the prediction of a protein's 3D structure, based only on its sequence. De novo synthesis of complex molecules from simple molecules in chemistry. De novo transcriptome assembly, the method of ...