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Virome refers to the assemblage of viruses [1][2] that is often investigated and described by metagenomic sequencing of viral nucleic acids [3] that are found associated with a particular ecosystem, organism or holobiont. The word is frequently used to describe environmental viral shotgun metagenomes. Viruses, including bacteriophages, are ...
The human virome is the total collection of viruses in and on the human body. [ 1 ][ 2 ][ 3 ] Viruses in the human body may infect both human cells and other microbes such as bacteria (as with bacteriophages). [ 4 ] Some viruses cause disease, while others may be asymptomatic. Certain viruses are also integrated into the human genome as ...
One such surveillance program is the Global Virome Project (GVP) an international collaborative research initiative based at the One Health Institute at the University of California, Davis. [ 29 ] [ 30 ] The GVP aims to boost infectious disease surveillance around the globe by using low cost sequencing methods in high risk countries to prevent ...
Metatranscriptomics is the set of techniques used to study gene expression of microbes within natural environments, i.e., the metatranscriptome. [1]While metagenomics focuses on studying the genomic content and on identifying which microbes are present within a community, metatranscriptomics can be used to study the diversity of the active genes within such community, to quantify their ...
Videomics (or vide-omics): A video analysis paradigm inspired by genomics principles, where a continuous image sequence (or video) can be interpreted as the capture of a single image evolving through time through mutations revealing 'a scene'. Multiomics: Integration of different omics in a single study or analysis pipeline. [26] 1.
Virome studies showed that most viral diversity was extreme and almost completely unknown. Rob Edwards and Rohwer proposed that a genome-based taxonomy was need to link the metagenomic data to the existing, morphology-based taxonomy. The controversial Phage Proteomic Tree was the resulting system and was featured in Life in Our Phage World (2015).
Sequencing is the only diagnostic method that will provide the full sequence of a virus genome. Hence, it provides the most information about very small differences between two viruses that would look the same using other diagnostic tests. Currently it is only used when this depth of information is required.
VirCapSeq. VirCapSeq is a system to broadly screen for all viral infections in vertebrates including humans. [1] It was designed by W. Ian Lipkin, Thomas Briese, and Amit Kapoor at Columbia University. [2] The researchers created a library of 2 million 50 to 100-mer oligonucleotides based on viral genome sequences described in the European ...