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Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is an incurable and invariably fatal neurodegenerative disease of cattle. [2] Symptoms include abnormal behavior, trouble walking, and weight loss. [1]
F. necrophorum is also a cause for lameness in sheep. Its infection is commonly called scald or foot rot. It can last for several years on land used by either sheep or cattle, and is found on most land of this type throughout the world. Due to its survival length in these areas, it is unrealistic to try to remove it.
TSEs in non-human mammals include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle – popularly known as "mad cow disease" – and chronic wasting disease (CWD) in deer and elk. The variant form of Creutzfeldt–Jakob disease in humans is caused by exposure to bovine spongiform encephalopathy prions. [4] [5] [6]
Sheep and goats are both small ruminants with cosmopolitan distributions due to their being kept historically and in modern times as grazers both individually and in herds in return for their production of milk, wool, and meat. [1] As such, the diseases of these animals are of great economic importance to humans.
Streptococcus bovis is a group of strains of Gram-positive bacteria, originally described as a species, [5] [6] that in humans is associated with urinary tract infections, endocarditis, sepsis, [7] and colorectal cancer. [8] S. bovis is commonly found in the alimentary tract of cattle, sheep, and other ruminants, [9] and may cause ruminal acidosis.
Scrapie and other transmissible spongiform encephalopathies are caused by prions. [19] Prions were determined to be the infectious agent because transmission is difficult to prevent with heat, radiation and disinfectants, the agent does not evoke any detectable immune response, and it has a long incubation period of between 18 months and 5 years. [20]
Bacterial meningitis – the kind that Beck contracted – is usually the most serious form, according to the Meningitis Research Foundation (MRF). The passing of a musical legend 🎸
Definite diagnosis of brucellosis requires the isolation of the organism from the blood, body fluids, or tissues, but serological methods may be the only tests available in many settings. Positive blood culture yield ranges between 40 and 70% and is less commonly positive for B. abortus than B. melitensis or B. suis .