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Equine recurrent uveitis (ERU) – also known as moon blindness, recurrent iridocyclitis, or periodic ophthalmia [1] – is an acute, nongranulomatous inflammation of the uveal tract of the eye, occurring commonly in horses of all breeds, worldwide. The causative factor is not known, but several pathogeneses have been suggested.
Uveitis: is a group of 30 intraocular inflammatory diseases [71] caused by infections, systemic diseases, organ-specific autoimmune processes, cancer or trauma. [72] That is, uveitis refers to a complex category of ocular diseases that can cause blindness if either left untreated or improperly diagnosed. [72]
A horse's genotype may be lp/lp (homozygous recessive), Lp/lp (heterozygous), or Lp/Lp (homozygous dominant). Horses without a dominant Lp gene do not exhibit leopard-complex traits, and cannot produce offspring with the Lp gene unless it is contributed by the other parent. Such horses are termed "non-characteristic" among Appaloosa horse ...
Uveitis is estimated to be responsible for approximately 10%-20% of the blindness in the United States. [ 36 ] For non-infectious uveitis, women are more likely (57%) to be affected than men, possibly due to their higher prevalence of related autoimmune diseases . [ 37 ]
The disease may progress to severe inflammation of the uveal layer of the eye (uveitis) with pain and sensitivity of the eyes to light. The affected eye often remains relatively painless while the inflammatory disease spreads through the uvea, where characteristic focal infiltrates in the choroid named Dalén–Fuchs nodules can be seen. The ...
Posterior synechia can be observed in cases of anterior uveitis secondary to severe to moderate bacterial keratitis. [2] Posterior synechia also cause glaucoma, but with a different mechanism. In posterior synechia, the iris adheres to the lens, blocking the flow of aqueous humor from the posterior chamber to the anterior chamber.
People taking Ozempic and Wegovy may be at increased risk of developing a debilitating eye condition that can cause irreversible vision loss, a study published in JAMA Ophthalmology finds.
For this reason, blindness in animals is a unique topic of study. In general, nocturnal or subterranean animals have less interest in the visual world, and depend on other sensory modalities . Visual capacity is a continuum, with humans falling somewhere in the center.