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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is a highly selective, orally bioavailable, and reversible direct inhibitor of free and clot-bound factor Xa. Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. [ 28 ]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  4. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  5. List of abbreviations used in medical prescriptions - Wikipedia

    en.wikipedia.org/wiki/List_of_abbreviations_used...

    metered dose inhaler m.d.u. more dicto utendus: to be used as directed mEq milliequivalent mg milligram mg/dL milligrams per deciliter MgSO4 magnesium sulfate: may be confused with "MSO4", spell out "magnesium sulfate" midi at midday min. minimum [or] minim [or] minutum: minimum [or] minim [or] minute mist. mistura: mixture

  6. When Is the Best Time to Take Metformin? - AOL

    www.aol.com/best-time-metformin-141700387.html

    The same advice goes here, too: If you take metformin twice or three times a day, aim to take it at the same times each day. ... But if it’s close to the time of your next dose, skip the missed ...

  7. I Missed My 2nd Vaccine Shot: What Do I Do Now? - AOL

    www.aol.com/missed-2nd-vaccine-shot-now...

    How to avoid missing your second dose Leave your first vaccine appointment with a date and time for the second appointment. This should happen automatically but, if not, ask for one and make sure ...

  8. Chuck Lorre Shares Heartfelt On-Air Tribute to L.A ...

    www.aol.com/chuck-lorre-shares-heartfelt-air...

    Chuck Lorre is offering his thanks to first responders.. At the end of his CBS comedy Georgie and Mandy’s First Marriage on Jan. 30, the vanity card written by the producer offered a message to ...

  9. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.