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  2. International unit - Wikipedia

    en.wikipedia.org/wiki/International_unit

    Multivitamins nutrition facts label showing that the international unit of, for example, vitamins D and E correspond to different gram values. In pharmacology, the international unit (IU) is a unit of measurement for the effect or biological activity of a substance, for the purpose of easier comparison across similar forms of substances.

  3. Calcifediol - Wikipedia

    en.wikipedia.org/wiki/Calcifediol

    Calcifediol is the precursor for calcitriol, the active form of vitamin D. [3] [4] It is synthesized in the liver, by hydroxylation of cholecalciferol (vitamin D 3) at the 25-position. [3] This enzymatic 25-hydroxylase reaction is mostly due to the actions of CYP2R1 , present in microsomes , although other enzymes such as mitochondrial CYP27A1 ...

  4. Cholecalciferol - Wikipedia

    en.wikipedia.org/wiki/Cholecalciferol

    The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...

  5. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    International units (IU) are based on measured biological activity or effect, or for some substances, a specified equivalent mass. [ citation needed ] Enzyme activity ( kat ) is commonly used for e.g. liver function tests like AST , ALT , LD and γ-GT in Sweden.

  6. CYP2R1 - Wikipedia

    en.wikipedia.org/wiki/CYP2R1

    The conversion of vitamin D, especially cholecalciferol, to 25(OH)D (calcifediol) is one of the key steps in the vitamin D hormonal system. The CYP2R1 enzymatic activity achieving this process was previously thought to be constitutively expressed and stable, so that serum 25(OH)D was a measure of the supply of vitamin D. [9]

  7. Previtamin D3 - Wikipedia

    en.wikipedia.org/wiki/Previtamin_D3

    Previtamin D 3 is an intermediate in the production of cholecalciferol (vitamin D 3). It is formed by the action of UV light, most specifically UVB light of wavelengths between 295 and 300 nm, acting on 7-dehydrocholesterol in the epidermal layers of the skin. [1] [2] [3] The B ring of the steroid nucleus structure is broken open, making a ...

  8. List of conversion factors - Wikipedia

    en.wikipedia.org/wiki/List_of_conversion_factors

    British thermal unit (60 °F) BTU 60 °F: ≈ 1.054 68 × 10 3 J: British thermal unit (63 °F) BTU 63 °F: ≈ 1.0546 × 10 3 J: calorie (International Table) cal IT: ≡ 4.1868 J = 4.1868 J: calorie (mean) cal mean: 1 ⁄ 100 of the energy required to warm one gram of air-free water from 0 °C to 100 °C at a pressure of 1 atm ≈ 4.190 02 J ...

  9. Calcium/cholecalciferol - Wikipedia

    en.wikipedia.org/wiki/Calcium/Cholecalciferol

    Calcium/cholecalciferol is a combination of a calcium salt and vitamin D 3 (cholecalciferol). It is used to prevent and treat lack of calcium and vitamin D in the elderly, as well for osteoporosis in combination with other medications. [1] [2]