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[8] [15] Nandrolone has strong anabolic effects and weak androgenic effects, which give them a mild side effect profile and make them especially suitable for use in women and children. [ 8 ] [ 15 ] [ 16 ] There are metabolites of Nandrolone that act as long-lasting prodrugs in the body, [ 8 ] such as 5α-Dihydronandrolone .
Side effects of nandrolone decanoate may include symptoms of masculinization like acne, increased hair growth, and voice changes. [3] The medication is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).
[18] [19] Nandrolone decanoate is approved for this use. [20] Although they have been indicated for this indication, AAS saw very little use for this purpose due to their virilizing side effects. [18] [21] Aiding weight gain following surgery or physical trauma, during chronic infection, or in the context of unexplained weight loss. [22] [23]
The androgens used for androgen replacement in women include testosterone (and esters), prasterone (dehydroepiandrosterone; DHEA) (and the ester prasterone enanthate), methyltestosterone, nandrolone decanoate, and tibolone, among others. [16
It was the first nandrolone ester to be introduced, followed by nandrolone decanoate in 1962, and has been one of the most widely used nandrolone esters. [3] [14] However, in more recent times, the drug has been largely superseded by nandrolone decanoate, which is longer-acting and more convenient to use.
[1] [2] [3] It is an androgen prohormone of nandrolone and of other 19-norandrostanes. [ 1 ] [ 2 ] [ 3 ] 19-Nor-5-androstenedione, 19-nor-5-androstenediol , and other 19-norandrostane prohormones were considered to be nutritional supplements and were sold over-the-counter in the United States as a result of the Dietary Supplement Health and ...
Norclostebol (INN Tooltip International Nonproprietary Name; brand name Lentabol; former developmental code names SKF-6611, CP-73) is a synthetic androgen and anabolic steroid (AAS) that was derived from nandrolone. [1] [2] [3] It was described in the literature in 1957. [1] Norclostebol is also used as an ester, norclostebol acetate (brand ...
Dimethyltrienolone (developmental code name RU-2420) is a synthetic, orally active, and extremely potent anabolic–androgenic steroid (AAS) and 17α-alkylated 19-nortestosterone (nandrolone) derivative which was never marketed for medical use. [1]