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Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]
The symptoms may include flu-like symptoms, trouble sleeping, nausea, poor balance, sensory changes, akathisia, intrusive thoughts, depersonalization and derealization, mania, anxiety, and depression. [2] [3] [4] The problem usually begins within three days [2] and may last for several weeks or months. [4] Psychosis may rarely occur. [2]
This was once thought to be the mechanism that resulted in improvement of depression symptoms, [2] however more recent systematic review of the academic literature has established that there is no correlation between 5-HT concentration or activity in the brain and depressive symptoms. [3]
Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram). Effectiveness and side effect rates can vary between SSRIs. As such, your healthcare provider may suggest ...
Post-SSRI sexual dysfunction (PSSD) [63] [64] refers to a set of symptoms reported by some people who have taken SSRIs or other serotonin reuptake-inhibiting (SRI) drugs, in which sexual dysfunction symptoms persist for at least three months [65] [66] [67] after ceasing to take the drug. The status of PSSD as a legitimate and distinct pathology ...
Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [4] [5] [2] Symptoms in mild cases include high blood pressure and a fast heart rate; usually without a fever. [2]
[20] [55] For children and adolescents with moderate-to-severe depressive disorder, fluoxetine seems to be the best treatment (either with or without cognitive behavioural therapy) but more research is needed to be certain. [43] [44] [56] [55] Sertraline, escitalopram, duloxetine might also help in reducing symptoms. [55]
Dysthymia (/ d ɪ s ˈ θ aɪ m i ə / dihs-THIY-mee-uh), also known as persistent depressive disorder (PDD), [3] is a mental and behavioral disorder, [5] specifically a disorder primarily of mood, consisting of similar cognitive and physical problems as major depressive disorder, but with longer-lasting symptoms.