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Purpura (/ ˈ p ɜːr p jʊər ə / [1]) is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure. The spots are caused by bleeding underneath the skin secondary to platelet disorders, vascular disorders, coagulation disorders, or other causes. [ 2 ]
Inflammation-induced damage to the skin's blood vessels causes palpable purpura. Palpable purpura is the clinical manifestation of leukocytoclastic vasculitis, which can be idiopathic or linked to sepsis, reactions to drugs, connective tissue diseases, cryoglobulinemia, hepatitis C or B infection, or underlying cancers
Schamberg's disease, (also known as "progressive pigmentary dermatosis of Schamberg", [1] "purpura pigmentosa progressiva" (PPP), [1] and "Schamberg's purpura" [1]) is a chronic discoloration of the skin found in people of all ages, usually only affecting the feet, legs or thighs or a combination. It may occur as a single event or subsequent ...
Livedo reticularis is a common skin finding consisting of a mottled reticulated vascular pattern that appears as a lace-like purplish discoloration of the skin. [1] The discoloration is caused by reduction in blood flow through the arterioles that supply the cutaneous capillaries, resulting in deoxygenated blood showing as blue discoloration ().
A petechia (/ p ɪ ˈ t iː k i ə /; [1] pl.: petechiae) is a small red or purple spot (≤4 mm in diameter) that can appear on the skin, conjunctiva, retina, and mucous membranes which is caused by haemorrhage of capillaries. [2] [3] The word is derived from Italian petecchia 'freckle', of obscure origin. [1]
Retiform purpura is a cutaneous morphology characterized by a branching , non-blanching patch, plaque, or lesion that develops when blood vessels supplying the skin become obstructed. [ 2 ] [ 3 ] This blockage leads to downstream cutaneous ischemia , or insufficient blood supply to the skin, causing purpura , necrosis , and potentially ...
All forms of vasculitis, even large vessel vasculitides, may cause skin manifestations. The most common skin manifestations include purpura , nodules , livedo reticularis , skin ulcers , and purpuric urticaria .
Purpura fulminans is an acute, often fatal, thrombotic disorder which manifests as blood spots, bruising and discolouration of the skin resulting from coagulation in small blood vessels within the skin and rapidly leads to skin necrosis and disseminated intravascular coagulation.
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