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Chloroquine retinopathy is a form of toxic retinopathy (damage of the retina) caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. [3]
Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth, often in the form of hydroxychloroquine sulfate. [3]
Drug-induced pigmentation of the skin may occur as a consequence of drug administration, and the mechanism may be postinflammatory hyperpigmentation in some cases, but frequently is related to actual deposition of the offending drug in the skin. [2]: 125–6 The incidence of this change varies, and depends on the type of medication involved.
One of the most notable scientific papers that first popularized hydroxychloroquine as a COVID-19 treatment was retracted from its journal due to ethical and methodological issues. Retractions in ...
The latest evidence shows no benefit to the drug when used in very sick patients.
We’ve rounded up the best, expert-recommended products to treat hyperpigmentation in dark skin, including cleansers, serums, moisturizers, and more. 13 expert-approved products for treating ...
A World Health Organization infographic that states that hydroxychloroquine does not prevent illness or death from COVID-19. Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [64] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [65]
Treatments include topical steroids, [16] cyclophosphamide, [17] dapsone, [13] and hydroxychloroquine. [14] Outlook ... hyperpigmentation may linger for a while. [18]