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Decidualization is a process that results in significant changes to cells of the endometrium in preparation for, and during, pregnancy. This includes morphological and functional changes (the decidual reaction ) to endometrial stromal cells (ESCs), the presence of decidual white blood cells (leukocytes), and vascular changes to maternal arteries.
Decidualization includes the process of differentiation of the spindle-shape stromal fibroblasts into the plump secretory decidual cells, which create a pericellular extracellular matrix rich in fibronectin and laminin (similar to epithelial cells). Vascularity, as well as vascular permeability, is enhanced in the decidualizing endometrium.
Before the fertilized ovum reaches the uterus, the mucous membrane of the body of the uterus undergoes important changes and is then known as the decidua.The thickness and vascularity of the mucous membrane are greatly increased; its glands are elongated and open on its free surface by funnel-shaped orifices, while their deeper portions are tortuous and dilated into irregular spaces.
The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus.It has a basal layer and a functional layer: the basal layer contains stem cells which regenerate the functional layer. [1]
Stromal tissue falls into the "functional" class that contributes to the body's support and movement. The cells which make up stroma tissues serve as a matrix in which the other cells are embedded. [2] Stroma is made of various types of stromal cells. Examples of stroma include: stroma of iris; stroma of cornea; stroma of ovary; stroma of ...
Also gastrocoel. The central internal cavity of the gastrula in most animal embryos, fated to develop into the lumen of the digestive tube ; the primitive gut. The archenteron initially has only one open end, known as the blastopore. B birth blastocoel Also blastocoele, blastocele, cleavage cavity, and segmentation cavity. The fluid-filled or yolk -filled cavity that forms in the developing ...
Mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or medicinal signaling cells, are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give rise to marrow adipose tissue).
This new model, the most extensive one generated to date, revealed that features from two, seemingly contradictory, older models [10] [11] coexist in the structure. Notably, similar arrangements of helical elements of alternating handedness, often referred to as "parking garage" structures, were proposed to be present in the endoplasmic ...