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There’s a maximum daily dose, so it’s possible to take too much metformin. Metformin overdose can include the following symptoms: Abnormally fast or slow heartbeat
In patients with diabetes, this may be caused by several factors, such as too much or incorrectly timed insulin, too much or incorrectly timed exercise (exercise decreases insulin requirements) or not enough food (specifically glucose containing carbohydrates). The variety of interactions makes cause identification difficult in many instances.
Sterne was the first to try metformin on humans for the treatment of diabetes; he coined the name "Glucophage" (glucose eater) for the medication and published his results in 1957. [161] [168] Metformin became available in the British National Formulary in 1958. It was sold in the UK by a small Aron subsidiary called Rona. [169]
Type 1 diabetes, also known as "Juvenile-onset" Diabetes is increasing in children and adolescents under the age of 15. [128] Type 1 diabetes is an autoimmune disease where the body attacks the beta-cells produced by the pancreas; therefore, causing the body to have insulin deficiency. [129]
For type 2 diabetes, you may take a metformin tablet with meals two or three times a day. ... A 2020 meta-analysis of 21 trials found that metformin treatment could reduce BMI by one unit ...
Another small study on people without diabetes who were overweight or had obesity found that those taking metformin lost between 5.6 and 6.5 percent of their body weight. In contrast, the control ...
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