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TOL-463 is an anti-infective medication which is under development for the treatment of bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC) (vaginal yeast infection). [ 3 ] [ 1 ] [ 4 ] [ 2 ] It is a boric acid -based vaginal anti-infective enhanced with ethylenediaminetetraacetic acid (EDTA) which was designed to have improved activity ...
[5] [19] [21] [10] [22] [23] It is specifically used following treatment with or in combination with nitroimidazoles like metronidazole for recurrent bacterial vaginosis. [ 5 ] [ 22 ] [ 10 ] Although it has been reported to be effective and is widely used for this purpose, clinical studies of boric acid for treatment of bacterial vaginosis are ...
LACTIN-V is a live biopharmaceutical medication containing the vaginally important Lactobacillus crispatus which is under development for the treatment of bacterial vaginosis and recurrent urinary tract infections. [68] [69] [70] It has shown initial effectiveness in considerably reducing recurrence of bacterial vaginosis following antibiotic ...
Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. [10]
BV: bacterial vaginosis: BVM: bag valve mask (Ambu bag) BVP: biventricular pacing (see artificial pacemaker) bleomycin, vincristine, and cisplatin (chemotherapy regimen) BW: blood work (blood tests) birth weight: BWS: Beckwith-Wiedemann syndrome: Bx: biopsy: BZDs: benzodiazepines
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