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Deoxyribonuclease II (DNase II) is also known as acid deoxyribonuclease because it has optimal activity in the low pH environment of lysosomes where it is typically found in higher eukaryotes. Some forms of recombinant DNase II display a high level of activity in low pH in the absence of divalent metal ions, similar to eukaryotic DNase II. [7]
The skin of amphibians is a major site of respiration in all species for which measurements are available. [2] Cutaneous respiration is the sole respiratory mode of lungless salamanders (family Plethodontidae) which lack lungs entirely yet constitute the largest family of salamanders. Cutaneous respiration in frogs and other amphibians may be ...
Deoxyribonuclease II (EC 3.1.22.1, DNase II, pancreatic DNase II, deoxyribonucleate 3'-nucleotidohydrolase, pancreatic DNase II, acid deoxyribonuclease, acid DNase) is an endonuclease that hydrolyzes phosphodiester linkages of deoxyribonucleotide in native and denatured DNA, yielding products with 3'-phosphates and 5'-hydroxyl ends, which occurs as a result of single-strand cleaving mechanism. [1]
Some skin secretions are associated with body hair. Skin secretions originate from glands that in dermal layer of the epidermis. Sweat, a physiological aid to body temperature regulation, is secreted by eccrine glands. Sebaceous glands secrete the skin lubricant sebum. Sebum is secreted onto the hair shaft and it prevents the hair from splitting.
56629 Ensembl ENSG00000137976 ENSMUSG00000028185 UniProt Q8WZ79 Q66K39 Q9QY48 RefSeq (mRNA) NM_021233 NM_058248 NM_019957 RefSeq (protein) NP_067056 NP_490649 NP_067056.2 NP_064341 Location (UCSC) Chr 1: 84.4 – 84.42 Mb Chr 3: 146.29 – 146.32 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Deoxyribonuclease 2 beta is a protein that in humans is encoded by the DNASE2B gene ...
It is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. [3] Dornase alfa hydrolyzes the DNA present in sputum/mucus and reduces viscosity in the lungs, promoting improved clearance of secretions. [3] It is produced in Chinese hamster ovary cells. [3]
When dust is inhaled, the particles can collect in your lungs and lead to respiratory issues. For those with allergies, these particles can be inhaled and trigger annoying symptoms like sneezing ...
Red arrows indicate secreted lamellar bodies, and green arrows indicate lamellar bodies in the cytoplasm. Scale bar = 200 nm. In cell biology, lamellar bodies (otherwise known as lamellar granules, membrane-coating granules (MCGs), keratinosomes or Odland bodies) are secretory organelles found in type II alveolar cells in the lungs, and in keratinocytes in the skin.