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Travelers' diarrhea (TD) is a stomach and intestinal infection. TD is defined as the passage of unformed stool (one or more by some definitions, three or more by others) while traveling. [ 2 ] [ 3 ] It may be accompanied by abdominal cramps, nausea, fever, headache and bloating. [ 3 ]
Bacillary dysentery should not be confused with diarrhea caused by other bacterial infections. One characteristic of bacillary dysentery is blood in stool , [ 7 ] which is the result of invasion of the mucosa by the pathogen.
Enterotoxigenic Escherichia coli (ETEC) is a type of Escherichia coli and one of the leading bacterial causes of diarrhea in the developing world, [1] as well as the most common cause of travelers' diarrhea. [2] Insufficient data exists, but conservative estimates suggest that each year, about 157,000 deaths occur, mostly in children, from ETEC.
Enterotoxigenic E. coli (ETEC) produces a toxin that acts on the intestinal lining, and is the most common cause of traveler's diarrhea. Enteropathogenic E. coli (EPEC) can cause diarrhea outbreaks in newborn nurseries. Enteroaggregative E. coli (EAggEC) can cause acute and chronic (long-lasting) diarrhea in children.
As many individuals are asymptomatic carriers of D. fragilis, pathogenic and nonpathogenic variants are proposed to exist.A study of D. fragilis isolates from 60 individuals with symptomatic infection in Sydney, Australia, found all were infected with the same genotype, [4] which is the most common worldwide, but differed from the genotype first described from a North American isolate and ...
E.coli causes intestinal infections, some intestinal infections include diarrhea, fever and abdominal pain. Most severe cases can lead to bloody diarrhea, dehydration or even kidney failure. People with weakened immune systems, young children, older adults and pregnant women are at increased risks for developing these complications.
It is a common cause of diarrhea in those who are hospitalized and is frequently associated with antibiotic use. [32] Staphylococcus aureus infectious diarrhea may also occur in those who have used antibiotics. [33] Acute "traveler's diarrhea" is usually a type of bacterial gastroenteritis, while the persistent form is usually parasitic. [34]
For example, Shigella is a longstanding World Health Organization (WHO) target for vaccine development, and sharp declines in age-specific diarrhea/dysentery attack rates for this pathogen indicate that natural immunity does develop following exposure; thus, vaccination to prevent this disease should be feasible. The development of vaccines ...