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Anterior interosseous syndrome is a medical condition in which damage to the anterior interosseous nerve (AIN), a distal motor and sensory branch of the median nerve, classically with severe weakness of the pincer movement of the thumb and index finger, and can cause transient pain in the wrist (the terminal, sensory branch of the AIN innervates the bones of the carpal tunnel).
Cheiralgia paraesthetica (Wartenberg's syndrome) is a neuropathy of the hand generally caused by compression or trauma to the superficial branch of the radial nerve. [1] [2] The area affected is typically on the back or side of the hand at the base of the thumb, near the anatomical snuffbox, but may extend up the back of the thumb and index finger and across the back of the hand.
The neurogenic type is the most common and presents with pain, weakness, paraesthesia, and occasionally loss of muscle at the base of the thumb. [1] [2] The venous type results in swelling, pain, and possibly a bluish coloration of the arm. [2] The arterial type results in pain, coldness, and pallor of the arm. [2]
Diagnosis is supported if pain increases when the wrist is bent inwards while a person is grabbing their thumb within a fist. [4] [6] Treatment for de Quervain tenosynovitis focuses on reducing inflammation, restoring movement in the thumb, and maintaining the range of motion of the wrist, thumb, and fingers. [6]
The main symptoms are pain in the hand, numbness, and tingling in the thumb, index finger, middle finger, and the thumb side of the ring finger. [1] Symptoms are typically most troublesome at night. [2] Many people sleep with their wrists bent, and the ensuing symptoms may lead to awakening. [7]
With gamekeeper's thumb, where the ulnar collateral ligament (UCL) is damaged, thumb functional abilities may be diminished. [4] For fingertip deformities, such as in mallet finger, pain and fingernail disruption may also be observed. [13] Rheumatoid arthritis of the hands may cause hand deformities.