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This is calculated by dividing the PaO2 by the FiO2. Example: patient who is receiving an FiO2 of .5 (i.e., 50%) with a measured PaO2 of 60 mmHg has a PaO 2 /FiO 2 ratio of 120. In healthy lungs, the Horowitz index depends on age and usually falls between 350 and 450.
A P a O 2 /F I O 2 ratio less than or equal to 250 mmHg is one of the minor criteria for severe community acquired pneumonia (i.e., possible indication for inpatient treatment). A P a O 2 /F I O 2 ratio less than or equal to 333 mmHg is one of the variables in the SMART-COP risk score for intensive respiratory or vasopressor support in ...
The partial pressure of oxygen (pO 2) in the pulmonary alveoli is required to calculate both the alveolar-arterial gradient of oxygen and the amount of right-to-left cardiac shunt, which are both clinically useful quantities. However, it is not practical to take a sample of gas from the alveoli in order to directly measure the partial pressure ...
The oxygenation index is a calculation used in intensive care medicine to measure the fraction of inspired oxygen (FiO2) and its usage within the body. A lower oxygenation index is better - this can be inferred by the equation itself. As the oxygenation of a person improves, they will be able to achieve a higher PaO2 at a lower FiO2.
Further, the effects of gravity alter the flow of both blood and air through various heights of the lung. In the upright lung, both perfusion and ventilation are greatest at the base, but the gradient of perfusion is steeper than that of ventilation so V/Q ratio is higher at the apex than at the base. This means that blood flowing through ...
In respiratory physiology, the ventilation/perfusion ratio (V/Q ratio) is a ratio used to assess the efficiency and adequacy of the ventilation-perfusion coupling and thus the matching of two variables: V – ventilation – the air that reaches the alveoli; Q – perfusion – the blood that reaches the alveoli via the capillaries
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Hypoxemic respiratory failure with a ratio of arterial oxygen tension to fraction of inspired oxygen (PaO2/FiO2) of <100 mmHg despite optimization of the ventilator settings, including the fraction of inspired oxygen (FiO2), positive end-expiratory pressure (PEEP), and inspiratory to expiratory (I:E) ratio