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[7] [8] Oxazepam is used for the treatment of anxiety, [9] [10] insomnia, and to control symptoms of alcohol withdrawal syndrome. It is a metabolite of diazepam , prazepam , and temazepam , [ 11 ] and has moderate amnesic , anxiolytic , anticonvulsant , hypnotic , sedative , and skeletal muscle relaxant properties compared to other benzodiazepines.
Chlordiazepoxide, 5 mg capsules, are sometimes used as an alternative to diazepam for benzodiazepine withdrawal. Like diazepam, it has a long elimination half-life and long-acting active metabolites. [25] [69] Management of benzodiazepine dependence involves considering the person's age, comorbidity and the pharmacological pathways of ...
For withdrawal purposes, stabilisation with a long-acting agent such as diazepam is recommended before commencing withdrawal. Chlordiazepoxide (Librium), a long-acting benzodiazepine, is gaining attention as an alternative to diazepam in substance abusers dependent on benzodiazepines due to its decreased abuse potential. [16]
Benzodiazepines are the most commonly used medication for the treatment of alcohol withdrawal and are generally safe and effective in suppressing symptoms of alcohol withdrawal. [33] This class of medication is generally effective in symptoms control, but needs to be used carefully.
Diazepam. Also known as Valium, diazepam is another widely prescribed benzodiazepine that’s used to treat anxiety disorders, panic attacks, seizures (typically in combination with other drugs ...
Withdrawal is best managed by transferring the physically dependent patient to an equivalent dose of diazepam because it has the longest half-life of all of the benzodiazepines, is metabolised into long-acting active metabolites and is available in low-potency tablets, which can be quartered for smaller doses. [145]