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However, research does not show whether the binding leads to the harmful side effects from the drug. A sample of the drug Singulair made by Merck & Co. is seen in New York March 9, 2009
Singulair was a blockbuster product for Merck after its launch in 1998, offering relief ... However, Marschallinger said the new data bolsters reports from people who reported suffering side effects.
Uncommon side effects include fatigue and malaise, behavioral changes, paresthesias and seizures, muscle cramps, and nose bleeds. Rare (may affect up to 1 in 10,000 people taking montelukast) but serious side effects include behavioral changes (including suicidal thoughts), angioedema, erythema multiforme, and liver problems. [3] [14]
Zafirlukast is FDA-approved for the prevention and treatment of asthma in adults and children older than 5 years old. [1] Like other leukotriene receptor antagonists, zafirlukast is thought to be useful for the long-term treatment of asthma, but it is generally less effective than inhaled glucocorticoids as monotherapy (which are the standard of care) or long-acting beta-2 agonists in ...
An early magazine advertisement for Merck’s breakthrough asthma and allergy medicine, Singulair, featured a happy child, hanging upside-down from a tree. When the drug launched in 1998, its ...
Common side effects include sleepiness, dry mouth, cough, vomiting, and diarrhea. [3] Use in pregnancy appears safe but has not been well studied and use when breastfeeding is of unclear safety. [5] It is classified as a second-generation antihistamine and works by blocking histamine H 1-receptors. [6] [3]
Nasal polyps occur more frequently in men than women and are more common as people get older, increasing drastically after the age of 40. [6] Of people with chronic rhinosinusitis, 10% to 54% also have allergies. An estimated 40% to 80% of people with sensitivity to aspirin will develop nasal polyposis. [6]
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