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Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), previously known as chronic nonbacterial prostatitis, is long-term pelvic pain and lower urinary tract symptoms (LUTS) without evidence of a bacterial infection. [3] It affects about 2–6% of men. [3] Together with IC/BPS, it makes up urologic chronic pelvic pain syndrome (UCPPS). [4]
Opioid treatment for chronic low back pain increases the risk for lifetime illicit drug use [100] and the effect of long-term use of opioids for lower back pain is unknown. [101] For older people with chronic pain, opioids may be used in those for whom NSAIDs present too great a risk, including those with diabetes, stomach or heart problems.
Prazosin was a much better tolerated drug than phenoxybenzamine but the problem still remained that it lowered the blood pressure more than desired for a BPH treatment. [ 2 ] [ 8 ] Terazosin was the first long-lasting alpha 1 blocker approved by FDA to treat BPH.
Pelvic pain is a general term that may have many causes, listed below. The subcategorical term urologic chronic pelvic pain syndrome (UCPPS) is an umbrella term adopted for use in research into urologic pain syndromes associated with the male and female pelvis. [9]
Symptoms vary depending on the cause of the prostatic congestion. [8] [18] Lower back, groin, or abdomen pain; Pain or discomfort around the penis or testicles; Swelling or enlargement of the prostate; Difficulty urinating; Frequent urination or nocturia; Dysuria – pain during urination; Prostate palpitations; Tender prostate gland
Prostate cancer: Myelosuppression, diarrhoea, kidney failure, hypersensitivity, severe GI reactions (including perforation, ileus, colitis, etc.; all rare) and peripheral neuropathy Docetaxel: IV: As above. Breast cancer, non-small cell lung cancer, ovarian cancer, prostate cancer, squamous cell head and neck cancer and gastric cancer.
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