Search results
Results From The WOW.Com Content Network
Creatinine clearance (C Cr) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR. Creatinine clearance exceeds GFR due to creatinine secretion, [ 4 ] which can be blocked by cimetidine .
A commonly used surrogate marker for the estimation of creatinine clearance is the Cockcroft–Gault (CG) formula, which in turn estimates GFR in ml/min: [21] It is named after the scientists, the asthmologist Donald William Cockcroft (b. 1946) and the nephrologist Matthew Henry Gault (1925–2003), who first published the formula in 1976, and ...
Diagram showing the basic physiologic mechanisms of the kidney. The renal clearance ratio or fractional excretion is a relative measure of the speed at which a constituent of urine passes through the kidneys.
If filtration in the kidney is deficient, blood creatinine concentrations rise. Therefore, creatinine concentrations in blood and urine may be used to calculate the creatinine clearance (CrCl), which correlates approximately with the glomerular filtration rate (GFR). Blood creatinine concentrations may also be used alone to calculate the ...
Adult: 40 [143] 100, [5] [146] 200, [144] 900 [143] x10 6 /L 0.0: 0.75, [14] 2 ... May be complemented with creatinine clearance: 0.7, [175] 0.8 [175] 1.0, [175] 1.3 ...
The primary sign of augmented renal clearance is an increase in the creatinine clearance well above that which would be considered normal. Commonly, ARC is defined as a creatinine clearance of greater than 130 mL/min, but the effects of increased clearance on therapy are not directly correlated to a specific number.
For the adult male, the normal range is 0.6 to 1.2 mg/dl, or 53 to 106 μmol/L by the kinetic or enzymatic method, and 0.8 to 1.5 mg/dl, or 70 to 133 μmol/L by the older manual Jaffé reaction. For the adult female, with her generally lower muscle mass, the normal range is 0.5 to 1.1 mg/dl, or 44 to 97 μmol/L by the enzymatic method.
2 CrCl 3 + H 2 → 2 CrCl 2 + 2 HCl. or by electrolysis. On the laboratory scale, LiAlH 4, zinc, and related reductants produce chromous chloride from chromium(III) precursors: 4 CrCl 3 + LiAlH 4 → 4 CrCl 2 + LiCl + AlCl 3 + 2 H 2 2 CrCl 3 + Zn → 2 CrCl 2 + ZnCl 2. CrCl 2 can also be prepared by treating a solution of chromium(II) acetate ...