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Paroxetine, sold under the brand name Paxil among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [7] used to treat major depressive disorder, obsessive–compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), generalized anxiety disorder, and premenstrual dysphoric disorder. [7]
Hypomania, [7] [unreliable medical source] [8] [9] [unreliable medical source] may occur in as many as 8% of patients being treated with paroxetine. May be more common in those with bipolar disorder. Asthenia; Weight gain or loss. Usually gain, paroxetine tends to produce more weight gain than other SSRIs. [6]: 58 Confusion; Emotional lability ...
Black hair is the most common in Asia and Africa. [2] Though this characteristic can also be seen throughout Europe as well, it is considerably less common. [3] It can be found in Celtic populations such as in Ireland, Scotland and Wales. [4] Black hair can come in a variety of textures, just as any hair color.
Over two million prescriptions for paroxetine were written for children or adolescents in the US in 2002. [29]Funded by SmithKline Beecham, the acute phase of study 329 was an eight-week, double-blind, randomized clinical trial conducted in 12 university or hospital psychiatric departments in the United States and Canada between 1994 and 1997.
Paroxetine was the first drug to be approved for social anxiety disorder and it is considered effective for this disorder; sertraline and fluvoxamine were later approved for it as well. Escitalopram and citalopram are used off-label with acceptable efficacy, while fluoxetine is not considered to be effective for this disorder. [ 22 ]
The petition filed by over 20 consumer advocacy groups in 2022 that argued for the removal of Red Dye No. 3 from food and dietary supplements cited studies, the FDA's prior use of the Delaney ...
Additionally, some clinically used drugs such as chlorpheniramine, dextromethorphan, and methadone possess SRI properties secondarily to their primary mechanism of action(s) and this contributes to their side effect and drug interaction profiles. A closely related type of drug is a serotonin releasing agent (SRA), an example of which is ...
Paroxetine (3S,4R)-3-[(2H-1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine [34] Paroxetine belongs to the phenylpiperidines. They contain a phenylpiperidine skeleton which consists of a piperidine bound to a phenyl group. [34] F The most potent 5-HT re-uptake blocker. It's the most potent blocker of muscarinic receptors among the SSRIs.