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2000 Flushes was created by Al Eisen, founder of New Jersey–based Flushco, Inc. [1] According to the company, Eisen's wife asked him to clean the toilet; he hated the job and tried to find a better way. His initial experiment, a cup with chlorine weighted with rocks and installed in the toilet tank, worked well at keeping his toilet clean for ...
The reaction is informally termed Asian flush due to its frequent occurrence in East Asians, with approximately 30 to 50% of Chinese, Japanese, and Koreans showing characteristic physiological responses to drinking alcohol that includes facial flushing, nausea, headaches and a fast heart rate.
Megavitamin-B 6 syndrome, also known as hypervitaminosis B 6, vitamin B 6 toxicity, and vitamin B 6 excess, [a] is a medical condition characterized by adverse effects resulting from excessive intake of vitamin B 6.
Water toxicity can occur when someone drinks water faster than their body can process it, leading to dangerously low levels of sodium and other essential nutrients. For Munro, it started in May ...
The concentration in serum after a typical dose of paracetamol usually peaks below 30 mg/L, which equals 200 μmol/L. [45] Levels of 30–300 mg/L (200–2000 μmol/L) are often observed in overdose patients. Postmortem blood levels have ranged from 50 to 400 mg/L in persons dying due to acute overdosage.
Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [1] [2] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [3] [4] use).
It is originally invented by Flushco, Inc. in 1978, branded as 2000 Flushes (acquired and now owned by WD-40 Company [3] [4]). [5] Eventually, some other brands and companies such as S.C. Johnson Scrubbing Bubbles, [6] Clorox, [7] and Ty-D-Bol sold their own in-tank toilet cleaner tablets.
Since acetaldehyde is toxic and can no longer be metabolized to the less toxic acetic acid, the characteristic symptoms of coprine poisoning occur. However, as shown in the mechanism below, the covalent bonding is reversible, which is what allows symptoms to subside if no more alcohol is consumed.