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  2. Depression and immune function - Wikipedia

    en.wikipedia.org/wiki/Depression_and_immune_function

    In addition to evidence suggesting that inflammation is not sufficient for the development of major depression, evidence for a lack of complete overlap also comes from findings that depression often occurs without existing immune challenges, with social adversity appearing to cause depression without the requirement of underlying inflammation.

  3. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]

  4. Depression (physiology) - Wikipedia

    en.wikipedia.org/wiki/Depression_(physiology)

    In physiology and medicine, depression [1] refers to a lowering, in particular a reduction in a specific biological variable or the functions of an organ. It is the opposite of elevation. For example, it is possible to refer to "depressed thyroid function" or to a depression of blood flow in a particular area. Further examples:

  5. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Specialty Psychiatry ...

  6. Anhedonia - Wikipedia

    en.wikipedia.org/wiki/Anhedonia

    Anhedonia is a diverse array of deficits in hedonic function, including reduced motivation or ability to experience pleasure. [1] While earlier definitions emphasized the inability to experience pleasure, anhedonia is currently used by researchers to refer to reduced motivation, reduced anticipatory pleasure (wanting), reduced consummatory pleasure (liking), and deficits in reinforcement learning.

  7. Animal models of depression - Wikipedia

    en.wikipedia.org/wiki/Animal_models_of_depression

    It is difficult to develop an animal model that perfectly reproduces the symptoms of depression in patients. It is generic that 3 standards may be used to evaluate the reliability of an animal version of depression: the phenomenological or morphological appearances (face validity), a comparable etiology (assemble validity), and healing similarities (predictive validity).

  8. Endogenous depression - Wikipedia

    en.wikipedia.org/wiki/Endogenous_depression

    Endogenous depression is an atypical subclass of major depressive disorder (clinical depression). It could be caused by genetic and biological factors. [ 1 ] Endogenous depression occurs due to the presence of an internal (cognitive, biological) stressor instead of an external (social, environmental) stressor. [ 2 ]

  9. Tripartite Model of Anxiety and Depression - Wikipedia

    en.wikipedia.org/wiki/Tripartite_Model_of...

    Physiological hyperarousal is defined by increased activity in the sympathetic nervous system, in response to threat. [11] Physiological hyperarousal is unique to anxiety disorders. [ 2 ] [ 12 ] Some symptoms of physiological hyperarousal include: shortness of breath, feeling dizzy or lightheaded, dry mouth, trembling or shaking, and sweaty palms.