Search results
Results From The WOW.Com Content Network
This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid hormone receptors. It includes inhibitory , excitatory , and neurotrophic neurosteroids as well as pheromones and vomeropherines .
[3] [4] The term, neuroactive steroid refers to steroids that can be synthesized in the brain, or are synthesized by an endocrine gland, that then reach the brain through the bloodstream and have effects on brain function. [5] The term neuroactive steroids was first coined in 1992 by Steven Paul and Robert Purdy.
Side effects of brexanolone may include sedation, sleepiness, dry mouth, hot flashes, and loss of consciousness. [ 6 ] [ 11 ] It is a neurosteroid and acts as a positive allosteric modulator of the GABA A receptor , the major biological target of the inhibitory neurotransmitter γ-aminobutyric acid (GABA).
Zuranolone, sold under the brand name Zurzuvae, is a medication used for the treatment of postpartum depression. [5] [6] It is taken by mouth.[5]The most common side effects include drowsiness, dizziness, diarrhea, fatigue, nasopharyngitis, and urinary tract infection.
Main page; Contents; Current events; Random article; About Wikipedia; Contact us
Ganaxolone, sold under the brand name Ztalmy, is a medication used to treat seizures in people with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder. [1] [3] Ganaxolone is a neuroactive steroid gamma-aminobutyric acid (GABA) A receptor positive modulator.
THDOC is a potent positive allosteric modulator of the GABA A receptor, and has sedative, anxiolytic and anticonvulsant effects. [ 3 ] [ 4 ] [ 5 ] Changes in the normal levels of this steroid particularly during pregnancy and menstruation may be involved in some types of epilepsy ( catamenial epilepsy ) and premenstrual syndrome , [ 6 ] as well ...
Alfaxalone is used as an induction agent, an injectable anesthetic, and a sedative in animals. [5] While it is commonly used in cats and dogs, it has also been successfully used in rabbits, [6] horses, sheep, pigs, and exotics such as red-eared turtles, axolotl, green iguanas, marmosets, [7] and koi fish. [8]