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The safety of sulfonylurea therapy in pregnancy is unestablished. Prolonged hypoglycemia (4 to 10 days) has been reported in children borne to mothers taking sulfonylureas at the time of delivery. [18] Impairment of liver or kidney function increase the risk of hypoglycemia, and are contraindications.
2 Sulfonylureas (anti-diabetic agents) 3 Diuretics. 4 Anticonvulsants. 5 Dermatologicals. ... Download as PDF; Printable version; In other projects Wikidata item ...
Acetohexamide (trade name Dymelor) is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone. [ 1 ]
In MODY1 and MODY3, sulfonylureas are usually very effective, delaying the need for insulin treatment. Sulfonylureas are effective in the K ATP channel forms of neonatal-onset diabetes. The mouse model of MODY diabetes suggested that the reduced clearance of sulfonylureas stands behind their therapeutic success in human MODY patients, but ...
In those with a history of diabetes treated with insulin, glinides, or sulfonylurea, who demonstrate Whipple's triad, it is reasonable to assume the cause of hypoglycemia is due to insulin, glinides, or sulfonylurea use. [2] In those without a history of diabetes with hypoglycemia, further diagnostic testing is necessary to identify the cause. [2]
Sulfonylureas bind strongly to plasma proteins. Sulfonylureas are useful only in type 2 diabetes, as they work by stimulating endogenous release of insulin. They work best with patients over 40 years old who have had diabetes mellitus for under ten years. They cannot be used with type 1 diabetes, or diabetes of pregnancy.
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Download as PDF; Printable version; In other projects Wikidata item; ... Pages in category "Sulfonylurea herbicides" The following 5 pages are in this category, out ...