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Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [ 2 ] [ 3 ] Most people are infected by the virus as children, when the disease produces few or no symptoms. [ 2 ]
We still need to know exactly what part of the immune response offers protection – and how strong it needs to be to remain protective.
COVID-19 immunity, whether it’s from catching COVID or getting vaccinated against the virus, doesn’t last forever, explains John Sellick, D.O., an infectious disease expert and professor of ...
The term reactogenicity was coined by the US Food and Drug Administration (FDA). All vaccines can induce reactogenicity, but reactogenicity is more likely in vaccines containing an adjuvant, which is a chemical additive intended for enhancing the recipient's immune response to the antigen that is present in a vaccine.
N1-Methylpseudouridine is the methylated derivative of pseudouridine.It is used in in vitro transcription and for the production of RNA vaccines. [3] [4] In vertebrates, it stimulates significantly less activation of the innate immune response compared to uridine, [5] while the translation is stronger.
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Many vaccine candidates use adjuvants to enhance immunogenicity, as part of the delivery system or as an accompanying immune stimulant. [8] [9] Vaccine adjuvant formulations using aluminum salts or "alum" may be particularly effective for technologies using inactivated COVID-19 virus and for recombinant protein-based or vector-based vaccines ...
In the trial, the vaccine candidates were compared to a licensed influenza vaccine and the companies' updated COVID-19 vaccine given at the same visit. Pfizer, BioNtech say flu-COVID shot ...
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