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AL amyloidosis occurs in about 3–13 per million people per year and AA amyloidosis in about two per million people per year. [2] The usual age of onset of these two types is 55 to 60 years old. [2] Without treatment, life expectancy is between six months and four years. [2]
AL amyloidosis is a rare disease; only 1200 to 3200 new cases are reported each year in the United States, and between 500 and 600 in the UK. Two thirds of patients with AL amyloidosis are male and less than 5% of patients are under 40 years of age. [6] [19] [9]
AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of insoluble protein in the extracellular space of various tissues and organs. In AA amyloidosis, the deposited protein is serum amyloid A protein (SAA), an acute-phase protein which is normally soluble and whose plasma concentration is highest ...
The majority of treatment is aimed at preserving heart function and treating heart failure symptoms. [3] Light chain (AL-CM) Treatment: Since the cause of this subtype of cardiac amyloidosis is the excessive production of free light chains, the major goal of treatment is the reduction in concentration of light chains. [5]
"It lowers life expectancy by as much as 2.4 years compared to a healthy weight," said American Heart Association volunteer Latha P. Palaniappan, M.D., a professor of cardiovascular medicine at ...
Treatment: Steroids, ... radiation therapy [3] [6] Prognosis: Five-year survival rate 54% / life expectancy 6 ... People with amyloidosis have high levels of amyloid ...
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